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American Society of Microbiology ABMM Sample Questions (Q136-Q141):

NEW QUESTION # 136
A clinical microbiology laboratory is investigating a potential outbreak of Legionella pneumophila associated with a hospital's water system. The MOST appropriate environmental samples to collect for culture and comparison to clinical isolates would be:

• A. Sputum samples from asymptomatic healthcare workers.
• B. Air samples from patient rooms and common areas.
• C. Surface swabs from frequently touched objects.
• D. Water samples from showers, faucets, and cooling towers.

Answer: D

 

NEW QUESTION # 137
Chagas disease, characterized by acute Romana's sign and potential chronic cardiac and gastrointestinal complications, is caused by which vector-borne protozoan parasite?

• A. Trypanosoma cruzi
• B. Leishmania donovani
• C. Toxoplasma gondii
• D. Trypanosoma brucei gambiense

Answer: A

 

NEW QUESTION # 138
The direct fluorescent antibody (DFA) test is commonly used for the rapid detection of which respiratory pathogen directly from nasopharyngeal specimens?

• A. Legionella pneumophila (serogroup 1 in sputum)
• B. Bordetella pertussis
• C. Influenza virus
• D. Mycoplasma pneumoniae

Answer: B

 

NEW QUESTION # 139
An immunocompromised patient develops a disseminated fungal infection. Blood cultures are negative, but a serum galactomannan assay is strongly positive. A CT scan of the chest reveals multiple nodular lesions with a halo sign. Bronchoalveolar lavage (BAL) fluid is analyzed by PCR, yielding a positive result for Aspergillus fumigatus. The halo sign observed on the CT scan is primarily attributed to:

• A. Extensive granuloma formation surrounding fungal hyphae.
• B. Angioinvasion by Aspergillus hyphae leading to localized hemorrhage and necrosis.
• C. A hypersensitivity reaction in the lung parenchyma.
• D. Formation of thick-walled cysts containing fungal conidia.

Answer: B

 

NEW QUESTION # 140
During a primary infection with Epstein-Barr virus (EBV), the virus establishes latency in B lymphocytes.
The transition from lytic to latent infection is tightly regulated by viral gene expression. Which of the following viral proteins is crucial for the establishment and maintenance of EBV latency and is a key target in EBV-associated lymphomas?

• A. Epstein-Barr nuclear antigen 1 (EBNA1)
• B. Viral capsid antigen (VCA)
• C. Glycoprotein gp350
• D. Early antigen (EA)

Answer: A

 

NEW QUESTION # 141
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